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Nitration of the Pollen Allergen Bet v 1.0101 Enhances the Presentation of Bet v 1-Derived Peptides by HLA-DR on Human Dendritic Cells

Nitration of pollen derived allergens can occur by NO(2) and ozone in polluted air and it has already been shown that nitrated major birch (Betula verrucosa) pollen allergen Bet v 1.0101 (Bet v 1) exhibits an increased potency to trigger an immune response. However, the mechanisms by which nitration...

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Detalles Bibliográficos
Autores principales: Karle, Anette C., Oostingh, Gertie J., Mutschlechner, Sonja, Ferreira, Fatima, Lackner, Peter, Bohle, Barbara, Fischer, Gottfried F., Vogt, Anne B., Duschl, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279363/
https://www.ncbi.nlm.nih.gov/pubmed/22348091
http://dx.doi.org/10.1371/journal.pone.0031483