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Auditory Function in the Tc1 Mouse Model of Down Syndrome Suggests a Limited Region of Human Chromosome 21 Involved in Otitis Media

Down syndrome is one of the most common congenital disorders leading to a wide range of health problems in humans, including frequent otitis media. The Tc1 mouse carries a significant part of human chromosome 21 (Hsa21) in addition to the full set of mouse chromosomes and shares many phenotypes obse...

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Detalles Bibliográficos
Autores principales: Kuhn, Stephanie, Ingham, Neil, Pearson, Selina, Gribble, Susan M., Clayton, Stephen, Steel, Karen P., Marcotti, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279367/
https://www.ncbi.nlm.nih.gov/pubmed/22348087
http://dx.doi.org/10.1371/journal.pone.0031433