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Auditory Function in the Tc1 Mouse Model of Down Syndrome Suggests a Limited Region of Human Chromosome 21 Involved in Otitis Media
Down syndrome is one of the most common congenital disorders leading to a wide range of health problems in humans, including frequent otitis media. The Tc1 mouse carries a significant part of human chromosome 21 (Hsa21) in addition to the full set of mouse chromosomes and shares many phenotypes obse...
Autores principales: | Kuhn, Stephanie, Ingham, Neil, Pearson, Selina, Gribble, Susan M., Clayton, Stephen, Steel, Karen P., Marcotti, Walter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279367/ https://www.ncbi.nlm.nih.gov/pubmed/22348087 http://dx.doi.org/10.1371/journal.pone.0031433 |
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