miRNA-Mediated Relationships between Cis-SNP Genotypes and Transcript Intensities in Lymphocyte Cell Lines

In metazoans, miRNAs regulate gene expression primarily through binding to target sites in the 3′ UTRs (untranslated regions) of messenger RNAs (mRNAs). Cis-acting variants within, or close to, a gene are crucial in explaining the variability of gene expression measures. Single nucleotide polymorphi...

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Detalles Bibliográficos
Autores principales: Zhang, Wensheng, Edwards, Andrea, Zhu, Dongxiao, Flemington, Erik K., Deininger, Prescott, Zhang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279374/
https://www.ncbi.nlm.nih.gov/pubmed/22348086
http://dx.doi.org/10.1371/journal.pone.0031429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279374/
https://www.ncbi.nlm.nih.gov/pubmed/22348086
http://dx.doi.org/10.1371/journal.pone.0031429

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