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Cultured Subventricular Zone Progenitor Cells Transduced with Neurogenin-2 Become Mature Glutamatergic Neurons and Integrate into the Dentate Gyrus

We have previously shown that transplantation of immature DCX+/NeuN+/Prox1+ neurons (found in the neonatal DG), but not undifferentiated neuronal progenitor cells (NPCs) from ventral subventricular zone (SVZ), results in neuronal maturation in vivo within the dentate niche. Here we investigated whet...

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Detalles Bibliográficos
Autores principales: Chen, Xia, Lepier, Alexandra, Berninger, Benedikt, Tolkovsky, Aviva M., Herbert, Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279376/
https://www.ncbi.nlm.nih.gov/pubmed/22348101
http://dx.doi.org/10.1371/journal.pone.0031547