Direct inhibition of myosin II effectively blocks glioma invasion in the presence of multiple motogens

Anaplastic gliomas, the most common and malignant of primary brain tumors, frequently contain activating mutations and amplifications in promigratory signal transduction pathways. However, targeting these pathways with individual signal transduction inhibitors does not appreciably reduce tumor invas...

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Detalles Bibliográficos
Autores principales: Ivkovic, Sanja, Beadle, Christopher, Noticewala, Sonal, Massey, Susan C., Swanson, Kristin R., Toro, Laura N., Bresnick, Anne R., Canoll, Peter, Rosenfeld, Steven S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279383/
https://www.ncbi.nlm.nih.gov/pubmed/22219380
http://dx.doi.org/10.1091/mbc.E11-01-0039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279383/
https://www.ncbi.nlm.nih.gov/pubmed/22219380
http://dx.doi.org/10.1091/mbc.E11-01-0039

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