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Direct inhibition of myosin II effectively blocks glioma invasion in the presence of multiple motogens
Anaplastic gliomas, the most common and malignant of primary brain tumors, frequently contain activating mutations and amplifications in promigratory signal transduction pathways. However, targeting these pathways with individual signal transduction inhibitors does not appreciably reduce tumor invas...
Autores principales: | Ivkovic, Sanja, Beadle, Christopher, Noticewala, Sonal, Massey, Susan C., Swanson, Kristin R., Toro, Laura N., Bresnick, Anne R., Canoll, Peter, Rosenfeld, Steven S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279383/ https://www.ncbi.nlm.nih.gov/pubmed/22219380 http://dx.doi.org/10.1091/mbc.E11-01-0039 |
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