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The tumor suppressor Lgl1 regulates NMII-A cellular distribution and focal adhesion morphology to optimize cell migration

The Drosophila tumor suppressor Lethal (2) giant larvae (Lgl) regulates the apical–basal polarity in epithelia and asymmetric cell division. However, little is known about the role of Lgl in cell polarity in migrating cells. In this study we show direct physiological interactions between the mammali...

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Detalles Bibliográficos
Autores principales: Dahan, Inbal, Yearim, Ahuv, Touboul, Yarin, Ravid, Shoshana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279388/
https://www.ncbi.nlm.nih.gov/pubmed/22219375
http://dx.doi.org/10.1091/mbc.E11-01-0015