Endoplasmic reticulum stress regulation of the Kar2p/BiP chaperone alleviates proteotoxicity via dual degradation pathways

The unfolded protein response (UPR) monitors and maintains protein homeostasis in the endoplasmic reticulum (ER). In budding yeast, the UPR is a transcriptional regulatory pathway that is quiescent under normal conditions. Under conditions of acute ER stress, activation of UPR targets is essential f...

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Detalles Bibliográficos
Autores principales: Hsu, Chia-Ling, Prasad, Rupali, Blackman, Christie, Ng, Davis T. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279391/
https://www.ncbi.nlm.nih.gov/pubmed/22190740
http://dx.doi.org/10.1091/mbc.E11-04-0297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279391/
https://www.ncbi.nlm.nih.gov/pubmed/22190740
http://dx.doi.org/10.1091/mbc.E11-04-0297

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