The Rab21-GEF activity of Varp, but not its Rab32/38 effector function, is required for dendrite formation in melanocytes

Vacuolar protein sorting 9 (VPS9)–ankyrin-repeat protein (Varp) has recently been identified as an effector molecule for two small GTPases—Rab32 and Rab38—in the transport of a melanogenic enzyme tyrosinase-related protein 1 (Tyrp1) to melanosomes in melanocytes. Although Varp contains a Rab21–guani...

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Detalles Bibliográficos
Autores principales: Ohbayashi, Norihiko, Yatsu, Ayaka, Tamura, Kanako, Fukuda, Mitsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279394/
https://www.ncbi.nlm.nih.gov/pubmed/22171327
http://dx.doi.org/10.1091/mbc.E11-04-0324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279394/
https://www.ncbi.nlm.nih.gov/pubmed/22171327
http://dx.doi.org/10.1091/mbc.E11-04-0324

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