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The Rab21-GEF activity of Varp, but not its Rab32/38 effector function, is required for dendrite formation in melanocytes
Vacuolar protein sorting 9 (VPS9)–ankyrin-repeat protein (Varp) has recently been identified as an effector molecule for two small GTPases—Rab32 and Rab38—in the transport of a melanogenic enzyme tyrosinase-related protein 1 (Tyrp1) to melanosomes in melanocytes. Although Varp contains a Rab21–guani...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279394/ https://www.ncbi.nlm.nih.gov/pubmed/22171327 http://dx.doi.org/10.1091/mbc.E11-04-0324 |