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EPI64 interacts with Slp1/JFC1 to coordinate Rab8a and Arf6 membrane trafficking

Cell function requires the integration of cytoskeletal organization and membrane trafficking. Small GTP-binding proteins are key regulators of these processes. We find that EPI64, an apical microvillar protein with a Tre-2/Bub2/Cdc16 (TBC) domain that stabilizes active Arf6 and has RabGAP activity,...

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Detalles Bibliográficos
Autores principales: Hokanson, David E., Bretscher, Anthony P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279397/
https://www.ncbi.nlm.nih.gov/pubmed/22219378
http://dx.doi.org/10.1091/mbc.E11-06-0521