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LKB1 Destabilizes Microtubules in Myoblasts and Contributes to Myoblast Differentiation
BACKGROUND: Skeletal muscle myoblast differentiation and fusion into multinucleate myotubes is associated with dramatic cytoskeletal changes. We find that microtubules in differentiated myotubes are highly stabilized, but premature microtubule stabilization blocks differentiation. Factors responsibl...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279410/ https://www.ncbi.nlm.nih.gov/pubmed/22348111 http://dx.doi.org/10.1371/journal.pone.0031583 |