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Prevalence and Genetic Characterization of Pertactin-Deficient Bordetella pertussis in Japan
The adhesin pertactin (Prn) is one of the major virulence factors of Bordetella pertussis, the etiological agent of whooping cough. However, a significant prevalence of Prn-deficient (Prn(−)) B. pertussis was observed in Japan. The Prn(−) isolate was first discovered in 1997, and 33 (27%) Prn(−) iso...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279416/ https://www.ncbi.nlm.nih.gov/pubmed/22348138 http://dx.doi.org/10.1371/journal.pone.0031985 |