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MiRNA Genes Constitute New Targets for Microsatellite Instability in Colorectal Cancer
Mismatch repair-deficient colorectal cancers (CRC) display widespread instability at DNA microsatellite sequences (MSI). Although MSI has been reported to commonly occur at coding repeats, leading to alterations in the function of a number of genes encoding cancer-related proteins, nothing is known...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279428/ https://www.ncbi.nlm.nih.gov/pubmed/22348132 http://dx.doi.org/10.1371/journal.pone.0031862 |