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Angiotensin I–Converting Enzyme Type 2 (ACE2) Gene Therapy Improves Glycemic Control in Diabetic Mice

OBJECTIVE: Several clinical studies have shown the benefits of renin-angiotensin system (RAS) blockade in the development of diabetes, and a local RAS has been identified in pancreatic islets. Angiotensin I–converting enzyme (ACE)2, a new component of the RAS, has been identified in the pancreas, bu...

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Detalles Bibliográficos
Autores principales: Bindom, Sharell M., Hans, Chetan P., Xia, Huijing, Boulares, A. Hamid, Lazartigues, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279528/
https://www.ncbi.nlm.nih.gov/pubmed/20660625
http://dx.doi.org/10.2337/db09-0782