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Identification of De Novo Synthesized and Relatively Older Proteins: Accelerated Oxidative Damage to De Novo Synthesized Apolipoprotein A-1 in Type 1 Diabetes

OBJECTIVE: The accumulation of old and damaged proteins likely contributes to complications of diabetes, but currently no methodology is available to measure the relative age of a specific protein alongside assessment of posttranslational modifications (PTM). To accomplish our goal of studying the i...

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Detalles Bibliográficos
Autores principales: Jaleel, Abdul, Henderson, Gregory C., Madden, Benjamin J., Klaus, Katherine A., Morse, Dawn M., Gopala, Srinivas, Nair, K. Sreekumaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279529/
https://www.ncbi.nlm.nih.gov/pubmed/20622162
http://dx.doi.org/10.2337/db10-0371