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Genetic Link Between Obesity and MMP14-Dependent Adipogenic Collagen Turnover

OBJECTIVE: In white adipose tissue, adipocytes and adipocyte precursor cells are enmeshed in a dense network of type I collagen fibrils. The fate of this pericellular collagenous web in diet-induced obesity, however, is unknown. This study seeks to identify the genetic underpinnings of proteolytic c...

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Detalles Bibliográficos
Autores principales: Chun, Tae-Hwa, Inoue, Mayumi, Morisaki, Hiroko, Yamanaka, Itaru, Miyamoto, Yoshihiro, Okamura, Tomonori, Sato-Kusubata, Kaori, Weiss, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279534/
https://www.ncbi.nlm.nih.gov/pubmed/20660624
http://dx.doi.org/10.2337/db10-0073