NOX2 Deficiency Protects Against Streptozotocin-Induced β-Cell Destruction and Development of Diabetes in Mice

OBJECTIVE: The role of NOX2-containing NADPH oxidase in the development of diabetes is not fully understood. We hypothesized that NOX2 deficiency decreases reactive oxygen species (ROS) production and immune response and protects against streptozotocin (STZ)-induced β-cell destruction and developmen...

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Detalles Bibliográficos
Autores principales: Xiang, Fu-Li, Lu, Xiangru, Strutt, Brenda, Hill, David J., Feng, Qingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279537/
https://www.ncbi.nlm.nih.gov/pubmed/20627937
http://dx.doi.org/10.2337/db09-1562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279537/
https://www.ncbi.nlm.nih.gov/pubmed/20627937
http://dx.doi.org/10.2337/db09-1562

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