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Calcium Dobesilate Inhibits the Alterations in Tight Junction Proteins and Leukocyte Adhesion to Retinal Endothelial Cells Induced by Diabetes

OBJECTIVE: Calcium dobesilate (CaD) has been used in the treatment of diabetic retinopathy in the last decades, but its mechanisms of action are not elucidated. CaD is able to correct the excessive vascular permeability in the retina of diabetic patients and in experimental diabetes. We investigated...

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Detalles Bibliográficos
Autores principales: Leal, Ermelindo C., Martins, João, Voabil, Paula, Liberal, Joana, Chiavaroli, Carlo, Bauer, Jacques, Cunha-Vaz, José, Ambrósio, António F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279541/
https://www.ncbi.nlm.nih.gov/pubmed/20627932
http://dx.doi.org/10.2337/db09-1421