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Calcium Dobesilate Inhibits the Alterations in Tight Junction Proteins and Leukocyte Adhesion to Retinal Endothelial Cells Induced by Diabetes
OBJECTIVE: Calcium dobesilate (CaD) has been used in the treatment of diabetic retinopathy in the last decades, but its mechanisms of action are not elucidated. CaD is able to correct the excessive vascular permeability in the retina of diabetic patients and in experimental diabetes. We investigated...
Autores principales: | Leal, Ermelindo C., Martins, João, Voabil, Paula, Liberal, Joana, Chiavaroli, Carlo, Bauer, Jacques, Cunha-Vaz, José, Ambrósio, António F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279541/ https://www.ncbi.nlm.nih.gov/pubmed/20627932 http://dx.doi.org/10.2337/db09-1421 |
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