Insulin Transactivator MafA Regulates Intrathymic Expression of Insulin and Affects Susceptibility to Type 1 Diabetes

OBJECTIVE: Tissue-specific self-antigens are ectopically expressed within the thymus and play an important role in the induction of central tolerance. Insulin is expressed in both pancreatic islets and the thymus and is considered to be the primary antigen for type 1 diabetes. Here, we report the ro...

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Detalles Bibliográficos
Autores principales: Noso, Shinsuke, Kataoka, Kohsuke, Kawabata, Yumiko, Babaya, Naru, Hiromine, Yoshihisa, Yamaji, Kaori, Fujisawa, Tomomi, Aramata, Shinsaku, Kudo, Takashi, Takahashi, Satoru, Ikegami, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Immunology and Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279543/
https://www.ncbi.nlm.nih.gov/pubmed/20682694
http://dx.doi.org/10.2337/db10-0476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279543/
https://www.ncbi.nlm.nih.gov/pubmed/20682694
http://dx.doi.org/10.2337/db10-0476

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