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Central Nervous System Delivery of the Antipsychotic Olanzapine Induces Hepatic Insulin Resistance

OBJECTIVE: Olanzapine (OLZ) is an atypical antipsychotic whose clinical efficacy is hampered by side effects including weight gain and diabetes. Recent evidence shows that OLZ alters insulin sensitivity independent of changes in body weight and composition. The present study addresses whether OLZ-in...

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Detalles Bibliográficos
Autores principales: Martins, Paulo J.F., Haas, Michael, Obici, Silvana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279549/
https://www.ncbi.nlm.nih.gov/pubmed/20682682
http://dx.doi.org/10.2337/db10-0449