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Chronic Administration of the Glucagon-Like Peptide-1 Analog, Liraglutide, Delays the Onset of Diabetes and Lowers Triglycerides in UCD-T2DM Rats

OBJECTIVE: The efficacy of liraglutide, a human glucagon-like peptide-1 (GLP-1) analog, to prevent or delay diabetes in UCD-T2DM rats, a model of polygenic obese type 2 diabetes, was investigated. RESEARCH DESIGN AND METHODS: At 2 months of age, male rats were divided into three groups: control, foo...

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Detalles Bibliográficos
Autores principales: Cummings, Bethany P., Stanhope, Kimber L., Graham, James L., Baskin, Denis G., Griffen, Steven C., Nilsson, Cecilia, Sams, Anette, Knudsen, Lotte B., Raun, Kirsten, Havel, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279561/
https://www.ncbi.nlm.nih.gov/pubmed/20622169
http://dx.doi.org/10.2337/db09-1564