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Large Copy-Number Variations Are Enriched in Cases With Moderate to Extreme Obesity

OBJECTIVE: Obesity is an increasingly common disorder that predisposes to several medical conditions, including type 2 diabetes. We investigated whether large and rare copy-number variations (CNVs) differentiate moderate to extreme obesity from never-overweight control subjects. RESEARCH DESIGN AND...

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Detalles Bibliográficos
Autores principales: Wang, Kai, Li, Wei-Dong, Glessner, Joseph T., Grant, Struan F.A., Hakonarson, Hakon, Price, R. Arlen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279563/
https://www.ncbi.nlm.nih.gov/pubmed/20622171
http://dx.doi.org/10.2337/db10-0192