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Four novel UCP3 gene variants associated with childhood obesity: effect on fatty acid oxidation and on prevention of triglyceride storage

OBJECTIVE: The objective of the study was to look for uncoupling protein 3 (UCP3) gene variants in early-onset severe childhood obesity and to determine their effect on long-chain fatty acid oxidation and triglyceride storage. METHODS AND RESULTS: We identified four novel mutations in the UCP3 gene...

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Detalles Bibliográficos
Autores principales: Musa, C V, Mancini, A, Alfieri, A, Labruna, G, Valerio, G, Franzese, A, Pasanisi, F, Licenziati, M R, Sacchetti, L, Buono, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279655/
https://www.ncbi.nlm.nih.gov/pubmed/21544083
http://dx.doi.org/10.1038/ijo.2011.81