Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes

Ubiquitin and UBL (ubiquitin-like) modifiers are small proteins that covalently modify other proteins to alter their properties or behaviours. Ubiquitin modification (ubiquitylation) targets many substrates, often leading to their proteasomal degradation. NEDD8 (neural-precursor-cell-expressed devel...

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Detalles Bibliográficos
Autores principales: Hjerpe, Roland, Thomas, Yann, Chen, Jesse, Zemla, Aleksandra, Curran, Siobhan, Shpiro, Natalia, Dick, Lawrence R., Kurz, Thimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280039/
https://www.ncbi.nlm.nih.gov/pubmed/22004789
http://dx.doi.org/10.1042/BJ20111671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280039/
https://www.ncbi.nlm.nih.gov/pubmed/22004789
http://dx.doi.org/10.1042/BJ20111671

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