Depletion of the actin bundling protein SM22/transgelin increases actin dynamics and enhances the tumourigenic phenotypes of cells

BACKGROUND: SM22 has long been studied as an actin-associated protein. Interestingly, levels of SM22 are often reduced in tumour cell lines, while they are increased during senescence possibly indicating a role for SM22 in cell fate decisions via its interaction with actin. In this study we aimed to...

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Detalles Bibliográficos
Autores principales: Thompson, Oliver, Moghraby, Jeelan S, Ayscough, Kathryn R, Winder, Steve J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280177/
https://www.ncbi.nlm.nih.gov/pubmed/22257561
http://dx.doi.org/10.1186/1471-2121-13-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280177/
https://www.ncbi.nlm.nih.gov/pubmed/22257561
http://dx.doi.org/10.1186/1471-2121-13-1

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