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Genome-wide assessment of the carriers involved in the cellular uptake of drugs: a model system in yeast

BACKGROUND: The uptake of drugs into cells has traditionally been considered to be predominantly via passive diffusion through the bilayer portion of the cell membrane. The recent recognition that drug uptake is mostly carrier-mediated raises the question of which drugs use which carriers. RESULTS:...

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Detalles Bibliográficos
Autores principales: Lanthaler, Karin, Bilsland, Elizabeth, Dobson, Paul D, Moss, Harry J, Pir, Pınar, Kell, Douglas B, Oliver, Stephen G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280192/
https://www.ncbi.nlm.nih.gov/pubmed/22023736
http://dx.doi.org/10.1186/1741-7007-9-70