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Selective APRIL Blockade Delays Systemic Lupus Erythematosus in Mouse
SLE pathogenesis is complex, but it is now widely accepted that autoantibodies play a key role in the process by forming excessive immune complexes; their deposits within tissues leading to inflammation and functional damages. A proliferation inducing ligand (APRIL) is a member of the tumor necrosis...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280206/ https://www.ncbi.nlm.nih.gov/pubmed/22355399 http://dx.doi.org/10.1371/journal.pone.0031837 |