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Selective APRIL Blockade Delays Systemic Lupus Erythematosus in Mouse

SLE pathogenesis is complex, but it is now widely accepted that autoantibodies play a key role in the process by forming excessive immune complexes; their deposits within tissues leading to inflammation and functional damages. A proliferation inducing ligand (APRIL) is a member of the tumor necrosis...

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Detalles Bibliográficos
Autores principales: Huard, Bertrand, Tran, Ngoc Lan, Benkhoucha, Mahdia, Manzin-Lorenzi, Céline, Santiago-Raber, Marie-Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280206/
https://www.ncbi.nlm.nih.gov/pubmed/22355399
http://dx.doi.org/10.1371/journal.pone.0031837