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Defective Expression and Function of the Leukocyte Associated Ig-like Receptor 1 in B Lymphocytes from Systemic Lupus Erythematosus Patients

Systemic lupus erythematosus (SLE) is characterized by the production of a wide array of autoantibodies and dysregulation of B cell function. The leukocyte associated Immunoglobulin (Ig)-like receptor (LAIR)1 is a transmembrane molecule belonging to Ig superfamily which binds to different types of c...

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Detalles Bibliográficos
Autores principales: Colombo, Barbara M., Canevali, Paolo, Magnani, Ottavia, Rossi, Edoardo, Puppo, Francesco, Zocchi, Maria Raffaella, Poggi, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280211/
https://www.ncbi.nlm.nih.gov/pubmed/22355402
http://dx.doi.org/10.1371/journal.pone.0031903