Winnowing DNA for Rare Sequences: Highly Specific Sequence and Methylation Based Enrichment

Rare mutations in cell populations are known to be hallmarks of many diseases and cancers. Similarly, differential DNA methylation patterns arise in rare cell populations with diagnostic potential such as fetal cells circulating in maternal blood. Unfortunately, the frequency of alleles with diagnos...

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Detalles Bibliográficos
Autores principales: Thompson, Jason D., Shibahara, Gosuke, Rajan, Sweta, Pel, Joel, Marziali, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280224/
https://www.ncbi.nlm.nih.gov/pubmed/22355378
http://dx.doi.org/10.1371/journal.pone.0031597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280224/
https://www.ncbi.nlm.nih.gov/pubmed/22355378
http://dx.doi.org/10.1371/journal.pone.0031597

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