Intranasal Administration of poly(I:C) and LPS in BALB/c Mice Induces Airway Hyperresponsiveness and Inflammation via Different Pathways

BACKGROUND: Bacterial and viral infections are known to promote airway hyperresponsiveness (AHR) in asthmatic patients. The mechanism behind this reaction is poorly understood, but pattern recognizing Toll-like receptors (TLRs) have recently been suggested to play a role. MATERIALS AND METHODS: To e...

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Detalles Bibliográficos
Autores principales: Starkhammar, Magnus, Kumlien Georén, Susanna, Swedin, Linda, Dahlén, Sven-Erik, Adner, Mikael, Cardell, Lars Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280225/
https://www.ncbi.nlm.nih.gov/pubmed/22355412
http://dx.doi.org/10.1371/journal.pone.0032110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280225/
https://www.ncbi.nlm.nih.gov/pubmed/22355412
http://dx.doi.org/10.1371/journal.pone.0032110

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