Subfunctionalization reduces the fitness cost of gene duplication in humans by buffering dosage imbalances

BACKGROUND: Driven essentially by random genetic drift, subfunctionalization has been identified as a possible non-adaptive mechanism for the retention of duplicate genes in small-population species, where widespread deleterious mutations are likely to cause complementary loss of subfunctions across...

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Detalles Bibliográficos
Autores principales: Fernández, Ariel, Tzeng, Yun-Huei, Hsu, Sze-Bi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280233/
https://www.ncbi.nlm.nih.gov/pubmed/22168623
http://dx.doi.org/10.1186/1471-2164-12-604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280233/
https://www.ncbi.nlm.nih.gov/pubmed/22168623
http://dx.doi.org/10.1186/1471-2164-12-604

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