IGD Motifs, Which Are Required for Migration Stimulatory Activity of Fibronectin Type I Modules, Do Not Mediate Binding in Matrix Assembly

Picomolar concentrations of proteins comprising only the N-terminal 70-kDa region (70K) of fibronectin (FN) stimulate cell migration into collagen gels. The Ile-Gly-Asp (IGD) motifs in four of the nine FN type 1 (FNI) modules in 70K are important for such migratory stimulating activity. The 70K regi...

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Detalles Bibliográficos
Autores principales: Maurer, Lisa M., Annis, Douglas S., Mosher, Deane F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280255/
https://www.ncbi.nlm.nih.gov/pubmed/22355321
http://dx.doi.org/10.1371/journal.pone.0030615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280255/
https://www.ncbi.nlm.nih.gov/pubmed/22355321
http://dx.doi.org/10.1371/journal.pone.0030615

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