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RET PLCγ Phosphotyrosine Binding Domain Regulates Ca(2+) Signaling and Neocortical Neuronal Migration

The receptor tyrosine kinase RET plays an essential role during embryogenesis in regulating cell proliferation, differentiation, and migration. Upon glial cell line-derived neurotrophic factor (GDNF) stimulation, RET can trigger multiple intracellular signaling pathways that in concert activate vari...

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Detalles Bibliográficos
Autores principales: Lundgren, T. Kalle, Nakahata, Katsutoshi, Fritz, Nicolas, Rebellato, Paola, Zhang, Songbai, Uhlén, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280273/
https://www.ncbi.nlm.nih.gov/pubmed/22355350
http://dx.doi.org/10.1371/journal.pone.0031258