Identification of Stk25 as a Genetic Modifier of Tau Phosphorylation in Dab1-Mutant Mice

Hyperphosphorylation of the microtubule binding protein Tau is a feature of a number of neurodegenerative diseases, including Alzheimer's disease. Tau is hyperphosphorylated in the hippocampus of dab1-null mice in a strain-dependent manner; however, it has not been clear if the Tau phosphorylat...

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Detalles Bibliográficos
Autores principales: Matsuki, Tohru, Zaka, Mariam, Guerreiro, Rita, van der Brug, Marcel P., Cooper, Jonathan A., Cookson, Mark R., Hardy, John A., Howell, Brian W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280280/
https://www.ncbi.nlm.nih.gov/pubmed/22355340
http://dx.doi.org/10.1371/journal.pone.0031152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280280/
https://www.ncbi.nlm.nih.gov/pubmed/22355340
http://dx.doi.org/10.1371/journal.pone.0031152

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