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Selective Cholinergic Depletion in Medial Septum Leads to Impaired Long Term Potentiation and Glutamatergic Synaptic Currents in the Hippocampus

Cholinergic depletion in the medial septum (MS) is associated with impaired hippocampal-dependent learning and memory. Here we investigated whether long term potentiation (LTP) and synaptic currents, mediated by alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionate (AMPA) and N-methyl-D-aspartate (N...

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Detalles Bibliográficos
Autores principales: Kanju, Patrick M., Parameshwaran, Kodeeswaran, Sims-Robinson, Catrina, Uthayathas, Subramaniam, Josephson, Eleanor M., Rajakumar, Nagalingam, Dhanasekaran, Muralikrishnan, Suppiramaniam, Vishnu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280283/
https://www.ncbi.nlm.nih.gov/pubmed/22355337
http://dx.doi.org/10.1371/journal.pone.0031073