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Selective Cholinergic Depletion in Medial Septum Leads to Impaired Long Term Potentiation and Glutamatergic Synaptic Currents in the Hippocampus
Cholinergic depletion in the medial septum (MS) is associated with impaired hippocampal-dependent learning and memory. Here we investigated whether long term potentiation (LTP) and synaptic currents, mediated by alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionate (AMPA) and N-methyl-D-aspartate (N...
Autores principales: | Kanju, Patrick M., Parameshwaran, Kodeeswaran, Sims-Robinson, Catrina, Uthayathas, Subramaniam, Josephson, Eleanor M., Rajakumar, Nagalingam, Dhanasekaran, Muralikrishnan, Suppiramaniam, Vishnu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280283/ https://www.ncbi.nlm.nih.gov/pubmed/22355337 http://dx.doi.org/10.1371/journal.pone.0031073 |
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