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Reduced Retinal Function in the Absence of Na(v)1.6

BACKGROUND: Mice with a function-blocking mutation in the Scn8a gene that encodes Na(v)1.6, a voltage-gated sodium channel (VGSC) isoform normally found in several types of retinal neurons, have previously been found to display a profoundly abnormal dark adapted flash electroretinogram. However the...

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Detalles Bibliográficos
Autores principales: Smith, Benjamin J., Côté, Patrice D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280295/
https://www.ncbi.nlm.nih.gov/pubmed/22355369
http://dx.doi.org/10.1371/journal.pone.0031476