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Hepatitis B Virus X Protein Drives Multiple Cross-Talk Cascade Loops Involving NF-κB, 5-LOX, OPN and Capn4 to Promote Cell Migration

Hepatitis B virus X protein (HBx) plays an important role in the development of hepatocellular carcinoma (HCC). However, the mechanism remains unclear. Recently, we have reported that HBx promotes hepatoma cell migration through the upregulation of calpain small subunit 1 (Capn4). In addition, sever...

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Detalles Bibliográficos
Autores principales: Zhang, Xuan, You, Xiaona, Wang, Qi, Zhang, Tao, Du, Yumei, Lv, Na, Zhang, Zhao, Zhang, Shuai, Shan, Changliang, Ye, Lihong, Zhang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280298/
https://www.ncbi.nlm.nih.gov/pubmed/22355367
http://dx.doi.org/10.1371/journal.pone.0031458