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Discrepant Effects of Human Interferon-gamma on Clinical and Immunological Disease Parameters in a Novel Marmoset Model for Multiple Sclerosis

The core pathogenic process in the common marmoset model of multiple sclerosis (MS) is the activation of memory-like T cells specific for peptide 34 to 56 derived from the extracellular domain of myelin/oligodendrocyte glycoprotein (MOG(34-56)). Immunization with MOG(34-56) in incomplete Freund’s ad...

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Detalles Bibliográficos
Autores principales: Jagessar, S. Anwar, Gran, Bruno, Heijmans, Nicole, Bauer, Jan, Laman, Jon D., ‘t Hart, Bert A., Constantinescu, Cris S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280389/
https://www.ncbi.nlm.nih.gov/pubmed/22012268
http://dx.doi.org/10.1007/s11481-011-9320-5