Cargando…

Role of Complement 3a in the Synthetic Phenotype and Angiotensin II-Production in Vascular Smooth Muscle Cells From Spontaneously Hypertensive Rats

BACKGROUND: Spontaneously hypertensive rats (SHR)-derived vascular smooth muscle cells (VSMCs) show exaggerated growth with a synthetic phenotype and angiotensin II (Ang II)-production. To evaluate the contribution of complement 3 (C3) or C3a toward these abnormalities in SHR, we examined effects of...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Ying, Fukuda, Noboru, Ueno, Takahiro, Endo, Morito, Ikeda, Kazuya, Xueli, Zhou, Matsumoto, Taro, Soma, Masayoshi, Matsumoto, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280391/
https://www.ncbi.nlm.nih.gov/pubmed/22089112
http://dx.doi.org/10.1038/ajh.2011.214