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Mobility in the structure of E.coli recQ helicase upon substrate binding as seen from molecular dynamics simulations

RecQ helicases feature multiple domains in their structure, of which the helicase domain, the RecQ-Ct domain and the HRDC domains are well conserved among the SF2 helicases. The helicase domain and the RecQ-Ct domain constitute the catalytic core of the enzyme. The domain interfaces are the DNA bind...

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Detalles Bibliográficos
Autores principales: Pandey, Nishtha, Govardhan, Savitha, Pathak, Ravi Kant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280434/
https://www.ncbi.nlm.nih.gov/pubmed/22347776