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Marine Compounds Selectively Induce Apoptosis in Female Reproductive Cancer Cells but Not in Primary-Derived Human Reproductive Granulosa Cells

Anticancer properties of tyrindoleninone and 6-bromoisatin from Dicathais orbita were tested against physiologically normal primary human granulosa cells (HGC) and reproductive cancer cell lines. Tyrindoleninone reduced cancer cell viability with IC(50) values of 39 µM (KGN; a tumour-derived granulo...

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Detalles Bibliográficos
Autores principales: Edwards, Vicki, Benkendorff, Kirsten, Young, Fiona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280530/
https://www.ncbi.nlm.nih.gov/pubmed/22363221
http://dx.doi.org/10.3390/md10010064