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Tetrodotoxin-Bupivacaine-Epinephrine Combinations for Prolonged Local Anesthesia
Currently available local anesthetics have analgesic durations in humans generally less than 12 hours. Prolonged-duration local anesthetics will be useful for postoperative analgesia. Previous studies showed that in rats, combinations of tetrodotoxin (TTX) with bupivacaine had supra-additive effects...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280572/ https://www.ncbi.nlm.nih.gov/pubmed/22363247 http://dx.doi.org/10.3390/md9122717 |