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Crucial role of SLP-76 and ADAP for neutrophil recruitment in mouse kidney ischemia-reperfusion injury

Neutrophils trigger inflammation-induced acute kidney injury (AKI), a frequent and potentially lethal occurrence in humans. Molecular mechanisms underlying neutrophil recruitment to sites of inflammation have proved elusive. In this study, we demonstrate that SLP-76 (SH2 domain–containing leukocyte...

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Detalles Bibliográficos
Autores principales: Block, Helena, Herter, Jan M., Rossaint, Jan, Stadtmann, Anika, Kliche, Stefanie, Lowell, Clifford A., Zarbock, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280874/
https://www.ncbi.nlm.nih.gov/pubmed/22291096
http://dx.doi.org/10.1084/jem.20111493