Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine

Intestinal immunoglobulin A (IgA) ensures host defense and symbiosis with our commensal microbiota. Yet previous studies hint at a surprisingly low diversity of intestinal IgA, and it is unknown to what extent the diverse Ig arsenal generated by somatic recombination and diversification is actually...

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Detalles Bibliográficos
Autores principales: Lindner, Cornelia, Wahl, Benjamin, Föhse, Lisa, Suerbaum, Sebastian, Macpherson, Andrew J., Prinz, Immo, Pabst, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280880/
https://www.ncbi.nlm.nih.gov/pubmed/22249449
http://dx.doi.org/10.1084/jem.20111980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280880/
https://www.ncbi.nlm.nih.gov/pubmed/22249449
http://dx.doi.org/10.1084/jem.20111980

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