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Targeting glucose metabolism for cancer therapy

Cellular transformation is associated with the reprogramming of cellular pathways that control proliferation, survival, and metabolism. Among the metabolic changes exhibited by tumor cells is an increase in glucose metabolism and glucose dependence. It has been hypothesized that targeting glucose me...

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Detalles Bibliográficos
Autores principales: Hamanaka, Robert B., Chandel, Navdeep S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280882/
https://www.ncbi.nlm.nih.gov/pubmed/22330683
http://dx.doi.org/10.1084/jem.20120162