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Tailoring inputs to achieve maximal neuronal firing
We consider the constrained optimization of excitatory synaptic input patterns to maximize spike generation in leaky integrate-and-fire (LIF) and theta model neurons. In the case of discrete input kicks with a fixed total magnitude, optimal input timings and strengths are identified for each model u...
Autores principales: | Wang, Jiaoyan, Costello, Willie, Rubin, Jonathan E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280888/ https://www.ncbi.nlm.nih.gov/pubmed/22656323 http://dx.doi.org/10.1186/2190-8567-1-3 |
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